MAsculinizing Hormone Therapy

At Medimix Compound Pharmacy, we recognize that gender-affirming care is essential healthcare. We are proud to support transgender men, nonbinary individuals, and anyone seeking masculinization through custom-compounded testosterone therapies. Our team works with you and your healthcare provider to create formulations tailored to your specific goals, needs, and preferences.

What is Masculinizing Hormone Therapy?

Masculinizing hormone therapy (MHT) involves the use of testosterone to develop more masculine physical traits and reduce gender dysphoria. It’s commonly chosen by trans men, nonbinary individuals assigned female at birth (AFAB), and others seeking physical masculinization.

For many, MHT is a life-changing step toward living more authentically. At Medimix, we’re here to support that process with professional care, custom medications, and ongoing pharmacy support.

How Does MHT Work?

Testosterone is the main hormone used in masculinizing therapy. As levels rise, it triggers the development of secondary male sex characteristics, such as:

• A deeper voice

• Increased facial and body hair

• More muscle mass and strength

• Redistribution of body fat

• Cessation of menstruation

• Clitoral growth

• Increased skin oil (which may cause acne)

• Potential scalp hair thinning (in those genetically predisposed)

Everyone’s journey looks different—changes happen over time and vary based on your body, age, dose, and health. Our ability to custom-compound testosterone means you get a formulation optimized for your body and goals.

Getting Started with Testosterone Therapy

Here’s what the typical process looks like:

1. Initial consultation with a healthcare provider experienced in gender-affirming care

2. Medical evaluation and blood work to establish a safe baseline

3. Informed consent conversations about effects, risks, and expectations

4. Prescription for the appropriate testosterone type and dosage

5. Ongoing monitoring and lab work to ensure safety and effectiveness

We coordinate with your care team to ensure your therapy is smooth, supportive, and personalized. Our pharmacists can also help with administration tips, formulation changes, or any concerns that arise.

Supporting Trans and Nonbinary Identities

MHT plays a powerful role in supporting transmasculine people by:

• Helping you feel more aligned with your gender identity

• Reducing gender dysphoria

• Improving confidence, mental health, and social well-being

• Supporting you in living fully and authentically

Whether you’re trans, nonbinary, gender-diverse, or questioning—your experience is valid. We’re here to help you access the care you deserve in an inclusive, affirming environment.

MHT vs. Testosterone Replacement Therapy (TRT)

While both MHT and TRT involve testosterone, their goals differ:

• TRT: Prescribed to cisgender men with low testosterone, to restore typical male hormone levels.

• MHT: Prescribed to trans men and nonbinary people seeking masculinization as part of gender-affirming care.

At Medimix, we offer custom testosterone preparations for both purposes, adjusting formulations to match each person’s unique therapeutic goals.

Benefits & Possible Side Effects of Testosterone Therapy

Benefits:

• Masculine physical features

• Reduced gender dysphoria

• Improved mental health

• Better alignment with gender identity

• Increased comfort in social and personal settings

Possible Side Effects (to monitor with your provider):

• Acne and oily skin

• Changes in mood or libido

• Scalp hair thinning (if predisposed)

• Polycythemia (increased red blood cells)

• Blood pressure or cholesterol changes

When monitored properly, testosterone therapy is considered safe and effective. That’s why working with a knowledgeable team—including your provider and our pharmacists—is key.

What to Expect Over Time

Masculinization is gradual, much like going through puberty. While the timeline varies by person, here’s a general guide:

• First 3 months: Mood shifts, libido changes, skin becomes oilier

• 3–6 months: Facial and body hair starts developing, voice begins deepening

• 6–12 months: Muscle growth, cessation of periods, increased strength

• 1–2 years: Further masculinization, including fat redistribution

• 2–5+ years: Full effects of hormone therapy, with ongoing refinement

Monitoring for Safety

Your healthcare team will regularly check your:

• Testosterone levels

• Liver function and red blood cell count

• Cholesterol and blood pressure

• Emotional and physical well-being

These check-ins help guide dosage adjustments and ensure your therapy is working as intended. If changes are needed, Medimix can compound updated formulations with precision and care.

Types of Testosterone We Compound

We offer a variety of custom formulations, including:

Injections

• Intramuscular or subcutaneous options

• Most common and cost-effective

• Weekly or bi-weekly dosing

Gels and Creams

• Daily topical application

• More gradual absorption

• Custom concentrations available

• Ideal for those sensitive to commercial ingredients

Our pharmacists can walk you through the pros and cons of each method and help you find the right fit based on your comfort, goals, and lifestyle.

Custom Testosterone Therapy with Medimix

What sets Medimix apart?

• Customized strengths and delivery methods

• Combination formulations, if appropriate

• Preservative- and allergen-free options

• Solutions for absorption challenges

• Discreet, Canada-wide shipping

• Direct communication with your care provider

Our compounding lab in Langley is equipped to handle even the most specialized requests, ensuring your therapy is personalized and reliable.

A Collaborative Approach to Gender-Affirming Care

We believe hormone therapy should be a team effort. At Medimix, we work closely with:

• You – understanding your goals, concerns, and preferences

• Your healthcare provider – aligning on monitoring and dosage

• Our pharmacy team – ensuring accuracy, consistency, and support

Our goal is to help you feel confident, safe, and empowered throughout your MHT journey.